Skip to main content

Understanding cannabinoids


Cannabis is a medicinal plant with several proven benefits. Applied with expert supervision, it is a completely natural and safe remedy for a wide range of conditions. In your analysis, you will come across the term ‘cannabinoids’. You may also learn about terms such as THC and CBD, which are varieties of cannabinoids.

Cannabinoids are the artificial composites in cannabis flowers (the plant) which imitate compounds that our bodies produce naturally, called endocannabinoids – read more about the endocannabinoid system here. These compounds, if stimulated, maintain internal stability and health; in other words, they help with the communication between cells. When there is a problem in our endocannabinoid system, then you will experience repulsive symptoms such as nausea, anxiety, pain and depression.

Types of cannabinoids

All classes derive from cannabigerol-type composites and differ mainly in the way this precursor is cyclised. The classical cannabinoids are derived from their respective 2-carboxylic acids (2-COOH) by decarboxylation (catalyzed by radiation, brightness or alkaline circumstances).

Tetrahydrocannabinol (THC)

Tetrahydrocannabinol (THC) is the original psychoactive component of the cannabis plant. Delta-9-tetrahydrocannabinol (Δ9-THC, THC) and delta-8-tetrahydrocannabinol (Δ8-THC), mimic the action of anandamide, a neurotransmitter generated naturally in the body.

These two THCs produce the impacts associated with cannabis by binding to the CB1 cannabinoid receptors in the brain. THC appears to relieve moderate pain (analgesic) and to be neuroprotective, while also offering the potential to diminish neuroinflammation and to stimulate neurogenesis. THC has approximately equal sympathy for the CB1 and CB2 receptors.

Cannabidiol (CBD)

Cannabidiol (CBD) is not psychoactive and was considered not to affect the psychoactivity of THC. Though, recent evidence shows that smokers of cannabis with a higher CBD/THC ratio were less likely to encounter schizophrenia-like symptoms.

Cannabidiol has a limited affinity for CB1 and CB2 receptors but acts as an indirect antagonist of cannabinoid agonists. Lately, it was found to be an antagonist at the putative new cannabinoid receptor, GPR55, a GPCR expressed in the caudate nucleus and putamen. Cannabidiol has also been shown to act as a 5-HT1A receptor agonist. It appears to ease convulsion, inflammation, anxiety and nausea.  CBD has a higher sympathy for the CB2 receptor than for the CB1 receptor.

CBD assigns a precursor with THC and is the main cannabinoid in low-THC Cannabis strains. CBD seemingly plays a role in preventing the short-term memory loss associated with THC in mammals.
Some experimentation suggests that the antipsychotic effects of cannabidiol potentially represent a novel mechanism in the treatment of schizophrenia. Researchers at California Pacific Medical Center recognised CBD’s ability to ‘turn off’ the activity of ID1, the gene responsible for metastasis in breast and other types of cancers, including the particularly threatening triple negative breast cancer.

Cannabinol (CBN)
Cannabinol (CBN) is the initial product of  THC degradation and there is usually little of it in a fresh plant. CBN content increases as THC degenerates in storage and with exposure to light and air. It is only moderately psychoactive. Its similarity to the CB2 receptor is higher than for the CB1 receptor.

Cannabigerol (CBG)
Cannabigerol (CBG) is non-psychotomimetic although still affects the overall effects of cannabis. It appears as an α2-adrenergic receptor agonist, 5-HT1A receptor antagonist and CB1 receptor antagonist. It also connects to the CB2 receptor.

Tetrahydrocannabivarin (THCV)
Tetrahydrocannabivarin (THCV) is widespread in certain central Asian and southern African strains of cannabis. It is an antagonist of THC at CB1 receptors and attenuates the psychoactive impacts of THC.

Cannabidivarin (CBCV)
However, Cannabidivarin (CBDV) is usually a minor component of the cannabinoid profile, enhanced levels of CBDV have been reported in feral cannabis plants from the northwest Himalayas and in hashish from Nepal.

Cannabichromene (CBC)
Cannabichromene (CBC) is non-psychoactive and appears not to affect the psychoactivity of THC. More prevalent in tropical cannabis species. Effects include anti-inflammatory and analgesic.
Medicinal properties of cannabinoids


This table harmonises each cannabinoid with the medical value that it has.
This will help you work out which cannabinoids are best at treating which symptoms, e.g. eating/gastrointestinal disorders, pain, sleep disorders and more.

 Disclaimer: the principles contained here is not designed nor meant to be a substitute for professional medical advice, it is only achieved for educational confidences only. You should recognise full responsibility for the way you decide on to use this information.

How to Buy or Make your own. 
The BEST way to get the oil is by making it yourself at home, but if you are not able to do this, you are free to order from us, but it would take anywhere from 7 to 28 Days to reach you after the payment reflects on our end, depending on your location and other factors.
Alternatively  Fill in order Form and we will contact you:- Click here As you complete the form remember to make payment for speedy delivery:-  Kindly visit Checkout Now Here or add to cart on the Blog.


Popular posts from this blog

Is Cannabis Oil an Effective Treatment for Psoriasis?

Share on PintertOvervieOverview Cannabis oil is now being used to treat pain and conditions such as Crohn’s disease, glaucoma, and nausea from chemotherapy. The proof is mounting that cannabis oil may additionally  be effective in treating everything from sclerosis and Parkinson’s unwellness to psychosis and post-traumatic stress disorder. But can cannabis be used to treat psoriasis? What is psoriasis? Psoriasis could be a chronic autoimmune disease that causes the fast build-up of skin cells. The new skin cells are generated so quickly that they reach the surface of the skin before they’re mature. This immature buildup on the surface of the skin forms restless raised patches of silvery scales. Parts of your body may additionally  become inflamed, and you may have redness, swelling, and discomfort. About fifteen per cent of individuals WHO have skin condition can develop rheumatoid arthritis. This condition causes painful swelling and stiffness of the joints. If left untreated, i

WHAT IS CANNABIS OIL?

Cannabis oil is a thick, sticky,  resinous  substance made up of a high concentration of  cannabinoids , such as THC and CBD, extracted from the cannabis plant (Cannabis sativa or Cannabis indica). Cannabis oil is a cannabis based product  obtained by separating the resins from cannabis flowers  using a solvent extraction process . Cannabis oil can also be known as marijuana oil, weed oil, pot oil,  Rick Simpson Oil (RSO) , Full extract cannabis oil (FECO), honey oil, hash oil, dabs, shatter, or wax. Cannabis oil is the most potent of three main cannabis products, which are the actual cannabis flower (marijuana), resin (hashish), and oil (cannabis oil). Cannabis oil is the most concentrated form of the three main cannabis products. That is what makes cannabis oil the most potent. Cannabis Oil produced and sold by "dealers" can have many contaminants and lots of times have little or no THC in them. Most of the time cannabis oil available on the street should be avoided for med

Rick Simpson Oil for Arthritis

A Centuries-Long Remedy for Arthritis When Rick Simpsons oil is mentioned as a curative substance, its perceived benefits are very often limited to fighting cancer. However, hemp oil carries in it the cure to an unending list of maladies, major among which is Arthritis. When Rick Simpson,the leader of the Cannabis oil movement after whom the oil got named, started using the oil, he did not only cure his skin cancer. Simpson had been suffering Arthritis in his knees for years, and after starting to ingest the oil, he says that he lost the Arthritis completely. It is actually documented that marijuana extracts have been used for treating Arthritis ever since 2800 BC. Firstly, we need to clearly identify the disease. Arthritis is a disorder that affects the joints, which despite being more common among the elderly, can affect people of all ages. Today, more than 52 million people across North America suffer one of the two types of Arthritis. This disorder is characterized by joint