If you’ve been following a pulse on Rick Simpsons Oil in recent years, you’re apparently already keen to the fact that cannabis composites are demonstrating some promise in the lab.
We’re looking back at some of the analysis shedding light on a new avenue of medicine, one that examines the fascinating role our endocannabinoid system plays in neurodegenerative conditions like Alzheimer’s. Looking forward, just imagine what we will achieve once those legal barriers surrounding cannabis investigation are listed on a federal level.
1. THC Slows Buildup of Neural Plaques
One of the characterizing pathological markers of Alzheimer’s is the buildup of amyloid plaques, a toxic collection of peptides in the neural tissue. This 2008 research published in Molecular Pharmaceutics found that THC slowed this amyloid β-peptide (Aβ) overgrowth, a discovery that was again examined in a 2014 study that appeared in the Journal of Alzheimer’s Disease. The earlier authors even obtained a low dose of THC to be “a considerably more effective inhibitor of AChE-induced Aβ deposition than the recommended drugs for Alzheimer’s disease treatment, donepezil and tacrine, which reduced Aβ aggregation by only 22% and 7%, sequentially, at twice the application used in our studies.”
2. Cannabis Fights Inflammation
Extra contributor to the development of Alzheimer’s is inflammation around these amyloid plaques. A 2006 report printed in Neuroscience examined the role of the endocannabinoid system (ECS) in Alzheimer’s, as activation of CB1 receptor sites had an anti-inflammatory effect. Other study cited in a 2012 review restated its importance; one research found that mice bred without CB1 receptors underwent faster cognitive degeneration. The bond between the ECS and neurodegenerative diseases has yet to be advanced in human trials, but the premise of this preliminary research alone is supportive.
3. CBD Could Prevent Cell Death
THC isn’t the only composite cannabis has to offer for Alzheimer’s examination; the non-intoxicating cannabidiol – better known as CBD – has also mentioned at its benefits in preventing cell death. In 2004, researchers perceived CBD’s neuroprotective, anti-oxidative and anti-apoptotic properties, thus decreasing neurotoxicity caused by amyloid buildup. These phenomena were again examined in a 2009 report that explored promising avenues in cannabinoid therapy, including that which involves a combination of THC and CBD. Noting the synergistic potential of cannabis constituents like CBD and THC, the researchers presumed with cautious optimism:
“The great therapeutic value of CBD, either given alone or in connection with THC, obtains from the consideration that it represents a rare, if not unique, composite that is capable of producing neuroprotection by the combination of different types of properties (e.g., anti-glutamatergic effects, anti-inflammatory action and antioxidant effects) that almost cover all spectra of neurotoxic mechanisms that operate in neurodegenerative disorders (excitotoxicity, inflammatory events, oxidative injury, etc.).”
4. Cannabinoids Stimulate Cell Growth
So in addition to cannabis’ antioxidant, anti-inflammatory, and neuroprotective properties, it would emerge that cannabinoids may also play a role in the growth of neural tissue in the hippocampus – the area of the brain linked with memory. This mechanism known as “neurogenesis” was examined and addressed in a 2011 study, as well as in a 2007 report that inspected cannabinoids “supporting the brain’s intrinsic repair mechanisms.”
5. Staving Off Other Alzheimer’s Symptoms
One of the more compelling reasons for Rick Simpsons Oil is its ability to relieve other symptoms associated with Alzheimer’s, allowing patients to live happier and more functional lives. From appetite stimulation and weight control to motor functioning and anxiety reduction, the enhanced quality of life that cannabis may offer these patients should be enough to warrant rescheduling of these versatile cannabinoids.
Looking back at decades of research supporting cannabis’ therapeutic privileges in not only Alzheimer’s, but in cancer, pain, epilepsy, stress disorders, sleep disorders, MS, HIV/AIDS, glaucoma, fibromyalgia, gastrointestinal disorders, arthritis, anorexia, diabetes, spasticity, it’s thoroughly incomprehensible to see cannabis still ranked as a Schedule 1 substance among the likes of heroin.
Delights to all of the specialists out there making this analysis happen despite political barriers and pitfalls.
Disclaimer: the principles contained here is not designed nor meant to be a substitute for professional medical advice, it is only achieved for educational confidences only. You should recognise full responsibility for the way you decide on to use this information.